Predictive value of protein induced by absence of vitamin K absence or antagonist II, alpha-fetoprotein and gamma-glutamyltransferase/aspartate aminotransferase ratio for the diagnosis of hepatocellular carcinoma in transplantation candidates

Ekmen N., Akalin C., Akyildiz M.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.33, sa.2, ss.294-299, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1097/meg.0000000000001884
  • Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.294-299
  • Anahtar Kelimeler: alpha-fetoprotein, aspartate aminotransferase, gamma-glutamyl transferase, hepatocellular carcinoma, protein induced by vitamin K absence or antagonist II, BIOMARKERS
  • Gazi Üniversitesi Adresli: Evet

Özet

Objectives Alpha-fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) are used as tumour markers for the diagnosis of hepatocellular carcinoma (HCC). We investigate whether combined liver function marker such as gamma-glutamyl transferase (GGT) and aspartate aminotransferase (AST) with alpha-fetoprotein (AFP) and PIVKA-II increase their diagnostic predictive value in diagnosis of HCC.