Clinical Significance of HER2 Overexpression in Gastric and Gastroesophageal Junction Cancers


Baykara M., Benekli M., EKİNCİ Ö., Irkkan S. C. , Karaca H., Demirci U., ...More

JOURNAL OF GASTROINTESTINAL SURGERY, vol.19, no.9, pp.1565-1571, 2015 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 9
  • Publication Date: 2015
  • Doi Number: 10.1007/s11605-015-2888-y
  • Journal Name: JOURNAL OF GASTROINTESTINAL SURGERY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1565-1571
  • Keywords: GC, GEJCs, HER2, Prognosis, C-ERBB-2 PROTEIN EXPRESSION, C-ERB B-2, PROGNOSTIC-SIGNIFICANCE, GENE AMPLIFICATION, CLINICOPATHOLOGICAL FEATURES, GROWTH, TRASTUZUMAB, CARCINOMAS, SURVIVAL, ADENOCARCINOMA

Abstract

In this study, we investigated the rate of human epidermal growth factor receptor 2 (HER2) overexpression in gastric (GC) and gastroesophageal junction cancers (GEJCs) and the relationship with HER2 expression and clinical, pathological parameters and prognosis.