Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbits Laboratory investigation

KALE A., BÖRCEK A. Ö., Emmez H., Yildirim Z., Durdag E., Lortlar N., ...Daha Fazla

JOURNAL OF NEUROSURGERY-SPINE, cilt.15, sa.3, ss.228-237, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3171/2011.4.spine10583
  • Dergi Adı: JOURNAL OF NEUROSURGERY-SPINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.228-237
  • Anahtar Kelimeler: spinal cord injury, ischemia-reperfusion injury, neuroprotection, gabapentin, OXIDATION PROTEIN PRODUCTS, EXCITATORY AMINO-ACIDS, LIPID-PEROXIDATION, NITRIC-OXIDE, SUPEROXIDE-DISMUTASE, ESTROGEN-RECEPTOR, WHITE-MATTER, STRESS, RAT, ACTIVATION
  • Gazi Üniversitesi Adresli: Evet

Özet

Object. Extensive research has been focused on neuroprotection after spinal cord trauma to alleviate the effects of secondary injury. This study aims to investigate the neuroprotective effects of gabapentin in an experimental spinal cord ischemia reperfusion injury.