A Case of Tubulocystic Carcinoma Simultaneously Occurring with Clear Cell Type Renal Cell Carcinoma and Micropapillary Urothelial Carcinoma of Bladder

Gonul I. I. , Cakir A., Sozen S., Ataoglu O., Alkibay T.

SOUTHERN MEDICAL JOURNAL, cilt.102, sa.7, ss.754-757, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 102 Konu: 7
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1097/smj.0b013e3181a819c1
  • Sayfa Sayıları: ss.754-757


The coexistence of multiple and synchronous primary neoplasms in the genitourinary system has rarely been described in the literature. To our knowledge, this is the first report of a very rare tumor, a "tubulocystic carcinoma," simultaneously occurring with micropapillary urothelial carcinoma in the bladder and clear cell type renal cell carcinoma in the same kidney. Tubulocystic carcinoma is a recently entitled tumor. It had been thought to arise from the distal collecting duct for a period of time and was therefore named as a low-grade collecting duct carcinoma. Microscopically, the tumor is defined as being tubulocystic or having tubulopapillary architecture and a low nuclear grade with hobnail morphology. Its progression and treatment protocol are uncertain.