Akademik Veri Yönetim Sistemi
International Journal of Environmental Health Engineering, cilt.9, sa.14, ss.1-6, 2020 (Scopus)
Aim: This study is aimed to determine the disinfectant activity of Derdevice plus Y® and I&D Sept® against carbapenem‑resistant Klebsiella
pneumoniae (CRKP) isolates. Materials and Methods: The bactericidal activity of Derdevice plus Y® and I&D Sept® were tested in vitro
under clean and dirty conditions by a quantitative suspension test according to EN 13727. The effectiveness of the disinfectants was compared
with 10% sodium hypochlorite (NaOCl), 7% benzalkonium chloride (BC), 2% chlorhexidine digluconate (CHX), and 70% ethyl alcohol
(EtOH). After 1, 5, and 60 min of contact with the biocides, the colony‑forming units were counted, and the logarithmic reduction factor was
determined. Results: A dilution of 1/300 of Derdevice plus Y® disinfectant showed bactericidal activity against clinical isolates and standard
strains (growth reduction was ≥5 log10) after 5 and 60 min contact times and under clean and dirty conditions. A 100% concentration of I&D
Sept® showed a bactericidal effect within the contact time (60 min) under clean and dirty conditions with the reductions of ≥5 log10 and ≥3 log10,
respectively. Standard biocides such as BC, CHX, NaOCl, and EtOH showed marked effects after various contact times and the conditions
onto tested strains. Conclusions: The results of our study confirm that the biocides of Derdevice plus Y® and I&D Sept® used in our hospital
were found to be effective against K. pneumoniae isolates.