Evaluation of the antimicrobial activities of chlorhexidine gluconate, sodium hypochlorite and octenidine hydrochloride in vitro

TİRALİ R. E., Bodur H., Sipahi B., SUNGURTEKİN EKÇİ E.

AUSTRALIAN ENDODONTIC JOURNAL, cilt.39, sa.1, ss.15-18, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1111/j.1747-4477.2010.00266.x
  • Dergi Adı: AUSTRALIAN ENDODONTIC JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.15-18
  • Anahtar Kelimeler: chlorhexidine gluconate, irrigation solutions, octenidine hydrochloride, sodium hypochlorite, APICAL PERIODONTITIS, ENDODONTIC IRRIGANTS, PLAQUE-FORMATION, DENTAL PLAQUE, MOUTHRINSE, TEETH, ELIMINATION, ANTISEPTICS, GINGIVITIS, EFFICACY
  • Gazi Üniversitesi Adresli: Evet

Özet

The objective of this study was to compare the antimicrobial activity of sodium hypochlorite (NaOCl), chlorhexidine gluconate (CHX) and octenidine hydrochloride (OCT) in different concentrations against endodontic pathogens in vitro. Agar diffusion procedure was used to determine the antimicrobial activity of the tested materials. Enterococcus faecalis, Candida albicans and the mixture of these were used for this study. In the agar diffusion test, 5.25% NaOCl exhibited better antimicrobial effect than the other concentrations of NaOCl for all strains. All concentrations of OCT were effective against C. albicans and E. faecalis. Some 0.2% CHX was ineffective on all microorganisms. Antibacterial effectiveness of all experimental solutions decreased on the mixture of all strains. Decreasing concentrations of NaOCl resulted in significantly reduced antimicrobial effect.