Smoking and gingivitis: focus on inducible nitric oxide synthase, nitric oxide and basic fibroblast growth factor

Ozdemir B., Ozmeric N., Elgun S., Baris E.

JOURNAL OF PERIODONTAL RESEARCH, cilt.51, sa.5, ss.596-603, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1111/jre.12338
  • Dergi Adı: JOURNAL OF PERIODONTAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.596-603
  • Anahtar Kelimeler: fibroblast growth factor, gingivitis, nitric oxide, nitric oxide synthase, smoking, PERIODONTAL-DISEASE, ENDOTHELIAL-CELLS, EXPRESSION, NICOTINE, NEUTROPHIL, PATHWAY, SMOKERS, INHIBITION, ATTACHMENT, INCREASES
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Periodontal disease pathogenesis has been associated with smoking. Gingivitis is a mild and reversible form of periodontal disease and it tends to progress to periodontitis only in susceptible individuals. In the present study, we aimed to examine the impact of smoking on host responses in gingivitis and to evaluate and compare the inducible nitric oxide synthase (iNOS) activity in gingival tissue and NO and basic fibroblast growth factor (bFGF) levels in the gingival crevicular fluid of patients with gingivitis and healthy individuals.