Polymorphisms in the vitamin D receptor gene and risk of lung cancer

Doğan, İREM; Önen, HACER; Yurdakul, AHMET; Konaç, ECE; Öztürk, CAN; Varol, Ayhan; Ekmekci, Abdullah

Polymorphisms in the vitamin D receptor gene and risk of lung cancer

Doğan İ., Önen H. İ., Yurdakul A. S., Konaç E., Öztürk C., Varol A., ...Daha Fazla

MEDICAL SCIENCE MONITOR, cilt.15, 2009 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 15
Basım Tarihi: 2009
Dergi Adı: MEDICAL SCIENCE MONITOR
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: VDR, genetic polymorphisms, lung cancer, POSTMENOPAUSAL BREAST-CANCER, PROSTATE-CANCER, VDR GENE, ASSOCIATION, EPIDEMIOLOGY, PROGRESSION, EXPRESSION, HAPLOTYPES, CARCINOMA, GENOTYPE
Gazi Üniversitesi Adresli: Evet

Özet

Background: Differences between the individual variations in DNA may modulate lung cancer process. Many studies reported that Vitamin D Receptor (VDR) gene polymorphisms may influence the cancer risk due to their antiproliferative, antiangiogenic, antimetastatic and apoptoic effects.