Lack of association between the CYP11B2 gene polymorphism and preeclampsia, eclampsia, and the HELLP syndrome in Turkish women

PERÇİN, FERDA; Cetin, Meral; Pinarbasi, Ergun; Akgun, Egemen; Gurlek, Fatma; ÇETİN, ALİ

doi:10.1016/j.ejogrb.2005.08.030

Lack of association between the CYP11B2 gene polymorphism and preeclampsia, eclampsia, and the HELLP syndrome in Turkish women

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PERÇİN F. E., Cetin M., Pinarbasi E., Akgun E., Gurlek F., ÇETİN A.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol.127, no.2, pp.213-217, 2006 (SCI-Expanded)

Publication Type: Article / Article
Volume: 127 Issue: 2
Publication Date: 2006
Doi Number: 10.1016/j.ejogrb.2005.08.030
Journal Name: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.213-217
Gazi University Affiliated: Yes

Abstract

Objectives: It is possible that altered control of aldosterone synthase gene (CYP11B2) expression or translation may be responsible for. hypertension. Hypertension is one of the major components of preeclampsia. We present here a study investigating the association between the CYP11B2 gene polymorphism in the promoter region at the position of -344 and preeclampsia.