Effect of Cytokine Signaling 3 Gene Polymorphisms in Childhood Obesity.

Boyraz M., Yesilkaya E., Ezgu F. S., BİDECİ A., Dogan H., ULUCAN K., ...Daha Fazla

Journal of clinical research in pediatric endocrinology, cilt.8, sa.4, ss.452-460, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4274/jcrpe.3167
  • Dergi Adı: Journal of clinical research in pediatric endocrinology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.452-460
  • Anahtar Kelimeler: Cytokine signaling, polymorphism, obesity, children, TURKISH CHILDREN, INSULIN-RESISTANCE, METABOLIC SYNDROME, HEPATIC STEATOSIS, SOCS-3 GENE, ADOLESCENTS, SUPPRESSOR, PROMOTER, INFLAMMATION, EXPRESSION
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: Although polymorphisms in suppressor of cytokine signaling 3 (SOCS3) was reported to be related to obesity, Metabolic syndrome (MS), and type 2 diabetes mellitus in various adult studies, there is a lack of data in children. In this study, we examined eight reported polymorphisms of SOCS3 in obese Turkish children and adolescent with and without MS and compared the results with that of controls.