Atıf İçin Kopyala
Yilmaz T. U., YAZIHAN N., Dalgic A., Kaya E. E., Salman B., Kocak M., ...Daha Fazla
INDIAN JOURNAL OF MEDICAL RESEARCH, cilt.141, ss.807-815, 2015 (SCI-Expanded)
-
Yayın Türü:
Makale / Tam Makale
-
Cilt numarası:
141
-
Basım Tarihi:
2015
-
Doi Numarası:
10.4103/0971-5916.160713
-
Dergi Adı:
INDIAN JOURNAL OF MEDICAL RESEARCH
-
Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
-
Sayfa Sayıları:
ss.807-815
-
Anahtar Kelimeler:
Diazoxide, erythropoietin, glinbenclamide, hypoxia inducible factor-1 alpha, KATP channels, REPERFUSION INJURY, ISCHEMIA/REPERFUSION INJURY, SIGNALING PATHWAYS, MECHANISMS, KIDNEY, CARDIOPROTECTION, INFLAMMATION, PROTECTS, CELLS, HEART
-
Gazi Üniversitesi Adresli:
Hayır
Özet
Background & objectives: Erythropoietin (EPO) has cytoprotective and anti-apoptotic effects in pathological conditions, including hypoxia and ischaemia-reperfusion injury. One of the targets to protect against injury is ATP-dependent potassium (KATP) channels. These channels could be involved in EPO induced ischaemic preconditoning like a protective effect. We evaluated the cell cytoprotective effects of EPO in relation to KATP channel activation in the renal tubular cell culture model under hypoxic/normoxic conditions.