Expression of MUC1 and MUC2 mucins in gastric carcinomas: Their relationship with clinicopathologic parameters and prognosis

Akyurek N., Akyol G., Dursun A., Yamac D., Gunel N.

PATHOLOGY RESEARCH AND PRACTICE, vol.198, no.10, pp.665-674, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 198 Issue: 10
  • Publication Date: 2002
  • Doi Number: 10.1078/0344-0338-00318
  • Journal Name: PATHOLOGY RESEARCH AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.665-674
  • Keywords: MUC1, MUC2, gastric carcinoma, immunohistochemistry, prognosis, MEDIATED CELL-ADHESION, MOLECULAR-CLONING, CHROMOSOMAL LOCALIZATION, ANTIGEN EXPRESSION, EPITHELIAL MUCIN, GENE-EXPRESSION, EPISIALIN MUC1, BREAST-CANCER, HUMAN STOMACH, MUC5AC
  • Gazi University Affiliated: Yes

Abstract

The aim of this study was to investigate the relationship between MUC1 and MUC2 mucin expressions and clinicopathologic variables in gastric carcinomas with regard to survival times. MUC1 and MUC2 expressions were revealed immunohistochemically in 143 gastric carcinomas. Of these 143 patients, follow-up data were available for 45 (median survival time of 30 months, ranging from 2 to 80 months).