Outcome of the Using Older Donors for Kidney Transplantation; Gazi University, Ankara Experience


Sozen H., Fidan K., ONARAN M. , Arinsoy T., Dalgic A.

TRANSPLANTATION PROCEEDINGS, vol.42, no.7, pp.2477-2478, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 7
  • Publication Date: 2010
  • Doi Number: 10.1016/j.transproceed.2010.04.044
  • Title of Journal : TRANSPLANTATION PROCEEDINGS
  • Page Numbers: pp.2477-2478

Abstract

The extreme organ shortage in Turkey has led to expansion of living and diseased donors. We retrospectively analyzed patient data to determine the outcomes of elderly donors. Among 2:10 donors, 28 (13.3%) were atleast >= 55 years old. In this group, 17 were from living and 11 from diseased donors. Mean cold ischemia time was 68 +/- 21 minutes. The immunosuppressive protocol consisted of induction therapy (simulect 20 mg on days 0 and 4) and immunosuppression with calcineurin inhibitors, mycophenolic acid, and steroids. Nine patients (32.6%) with delayed graft function (DGF) required transient hemodialysis. None of the recipients or their grafts were lost due to surgical complications. We noted 5 acute rejection episodes which were all reversed by pulse steroids. Mean creatinine levels at 1, 3, and 5 years were 1.7, 2.1 and 2.3 mg/dL respectively. Patient and graft survivals at 1, 3, and 5 years were 100%, 96%, and 92% and 100%, 92%, and 92%, respectively. Although 3.6% of recipients displayed DGF, it did not affect graft outcomes. In conclusion, kidney transplantation from older donors should be considered to be an option for kidney transplantation.