Bioactivity-guided isolation of flavonoids from Urtica dioica L. and their effect on endometriosis rat model


İlhan M., Ali Z., Khan I. A. , TAŞTAN H. , AKKOL E.

JOURNAL OF ETHNOPHARMACOLOGY, vol.243, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 243
  • Publication Date: 2019
  • Doi Number: 10.1016/j.jep.2019.112100
  • Title of Journal : JOURNAL OF ETHNOPHARMACOLOGY
  • Keywords: Urtica dioica, Stinging nettle, Endometriosis, Traditional medicine, Flavonoids, IN-VITRO, TRADITIONAL MEDICINE, PERITONEAL-FLUID, FOLK MEDICINE, GROWTH-FACTOR, AERIAL PARTS, MEDIATORS, GLYCOSIDES, EXTRACTS, AGONIST

Abstract

Ethnopharmacological relevance: Urtica dioica L. has been used traditionally for centuries. U. dioica leaves and roots are used as a blood purifier, emmenagogue, and diuretic, as well as to treat menstrual hemorrhage, rheumatism, and eczema. The present study aimed to evaluate the activity of U. dioica L. aerial parts in endometriosis rat model.