Bioactivity-guided isolation of flavonoids from Urtica dioica L. and their effect on endometriosis rat model


İlhan M., Ali Z., Khan I. A. , TAŞTAN H., AKKOL E.

JOURNAL OF ETHNOPHARMACOLOGY, vol.243, 2019 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 243
  • Publication Date: 2019
  • Doi Number: 10.1016/j.jep.2019.112100
  • Journal Name: JOURNAL OF ETHNOPHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Keywords: Urtica dioica, Stinging nettle, Endometriosis, Traditional medicine, Flavonoids, IN-VITRO, TRADITIONAL MEDICINE, PERITONEAL-FLUID, FOLK MEDICINE, GROWTH-FACTOR, AERIAL PARTS, MEDIATORS, GLYCOSIDES, EXTRACTS, AGONIST

Abstract

Ethnopharmacological relevance: Urtica dioica L. has been used traditionally for centuries. U. dioica leaves and roots are used as a blood purifier, emmenagogue, and diuretic, as well as to treat menstrual hemorrhage, rheumatism, and eczema. The present study aimed to evaluate the activity of U. dioica L. aerial parts in endometriosis rat model.