Another important contoversial issue of the Caldiran war that took place between Yavuz Sultan Selim and Shah Ismail is whether Tajlu Khanum, the wife of Shah Ismail, was taken as a captive by the Ottomans or not. This issue is presented by both Otoman and Safevid historians in terms of shame, honour, sexuality and psychological superiority. According to Ottoman documents, Tajlu Begum Hanim was taken as a captive and she was made to marry Tacizade Cafer Celebi, one of the Ottoman bureaucrats. As to the Safevid documents, they never mention about her captivity and it is only written that she was lost just for a few days. When Ottoman and Safevid documents are examined comparatively, it is understood that she was taken by Ottoman as a captive at least for a few days but later she was released and she returned to Shah Ismail. So it is impossible that she stayed in Anatolia and was made to marry Tacizade Cafer Celebi. Tajlu Khanum, one of the most influential people in the Palace of Shah Ismail, had a great influence on the Army and bureaucracy even after the death of Shah Ismail. Yet, during the last years of her life, she lost her importance, she was sent out of the harem and was exiled to Shiraz. In this article, the question of whether Tajlu Khanum was taken as captive by the Ottomans or not has been discussed and her biography has been given.