Rosuvastatin, a New Generation 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor, Reduces Ischemia/Reperfusion-Induced Spinal Cord Tissue Injury in Rats

Ucak, Alper; Onan, Burak; Guler, Adem; Sahin, Mehmet; Kilickaya, Oguz; Oztas, Emin; Uysal, Bulent; Arslan, Siddik; Yilmaz, Ahmet

doi:10.1016/j.avsg.2011.02.024

Rosuvastatin, a New Generation 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor, Reduces Ischemia/Reperfusion-Induced Spinal Cord Tissue Injury in Rats

Copy For Citation

Ucak A., Onan B., Guler A., Sahin M. A., Kilickaya O., Oztas E., ...More

ANNALS OF VASCULAR SURGERY, vol.25, no.5, pp.686-695, 2011 (SCI-Expanded)

Publication Type: Article / Article
Volume: 25 Issue: 5
Publication Date: 2011
Doi Number: 10.1016/j.avsg.2011.02.024
Journal Name: ANNALS OF VASCULAR SURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.686-695
Gazi University Affiliated: Yes

Abstract

Background: Severe neurological injury still represents one of the most devastating complications occurring after surgical repair of thoracoabdominal aneurysms. We aimed to investigate the role of rosuvastatin (RSV) against ischemia/reperfusion injury in an experimental model of spinal cord ischemia in rats.