Rosuvastatin, a New Generation 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor, Reduces Ischemia/Reperfusion-Induced Spinal Cord Tissue Injury in Rats


Ucak A., Onan B., Guler A., Sahin M. A., Kilickaya O., Oztas E., ...Daha Fazla

ANNALS OF VASCULAR SURGERY, cilt.25, sa.5, ss.686-695, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 5
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.avsg.2011.02.024
  • Dergi Adı: ANNALS OF VASCULAR SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.686-695
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Severe neurological injury still represents one of the most devastating complications occurring after surgical repair of thoracoabdominal aneurysms. We aimed to investigate the role of rosuvastatin (RSV) against ischemia/reperfusion injury in an experimental model of spinal cord ischemia in rats.