Rosuvastatin, a New Generation 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor, Reduces Ischemia/Reperfusion-Induced Spinal Cord Tissue Injury in Rats


Ucak A., Onan B., Guler A., Sahin M. A., Kilickaya O., Oztas E., ...More

ANNALS OF VASCULAR SURGERY, vol.25, no.5, pp.686-695, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 5
  • Publication Date: 2011
  • Doi Number: 10.1016/j.avsg.2011.02.024
  • Journal Name: ANNALS OF VASCULAR SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.686-695
  • Gazi University Affiliated: Yes

Abstract

Background: Severe neurological injury still represents one of the most devastating complications occurring after surgical repair of thoracoabdominal aneurysms. We aimed to investigate the role of rosuvastatin (RSV) against ischemia/reperfusion injury in an experimental model of spinal cord ischemia in rats.