Rosuvastatin, a New Generation 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor, Reduces Ischemia/Reperfusion-Induced Spinal Cord Tissue Injury in Rats

Ucak, Alper; Onan, Burak; Guler, Adem; Sahin, Mehmet; Kilickaya, Oguz; Oztas, Emin; Uysal, Bulent; Arslan, Siddik; Yilmaz, Ahmet

doi:10.1016/j.avsg.2011.02.024

Rosuvastatin, a New Generation 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor, Reduces Ischemia/Reperfusion-Induced Spinal Cord Tissue Injury in Rats

Atıf İçin Kopyala

Ucak A., Onan B., Guler A., Sahin M. A., Kilickaya O., Oztas E., ...Daha Fazla

ANNALS OF VASCULAR SURGERY, cilt.25, sa.5, ss.686-695, 2011 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 25 Sayı: 5
Basım Tarihi: 2011
Doi Numarası: 10.1016/j.avsg.2011.02.024
Dergi Adı: ANNALS OF VASCULAR SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.686-695
Gazi Üniversitesi Adresli: Evet

Özet

Background: Severe neurological injury still represents one of the most devastating complications occurring after surgical repair of thoracoabdominal aneurysms. We aimed to investigate the role of rosuvastatin (RSV) against ischemia/reperfusion injury in an experimental model of spinal cord ischemia in rats.