Genotoxicity of Anesthetics Evaluated In Vivo (Animals)


Braz M. G. , KARAHALİL B.

BIOMED RESEARCH INTERNATIONAL, vol.2015, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 2015
  • Publication Date: 2015
  • Doi Number: 10.1155/2015/280802
  • Title of Journal : BIOMED RESEARCH INTERNATIONAL

Abstract

The anesthesia has been improved all over the years. However, it can have impact on health, in both patients and animals anesthetized, as well as professionals exposed to inhaled anesthetics. There is continuing effort to understand the possible effects of anesthetics at molecular levels. Knowing the effects of anesthetic agents on genetic material could be a valuable basic support to better understand the possible mechanisms of these agents. Thus, the purpose of this review is to provide an overview on the genotoxic potential, evaluated in animal models, of many anesthetics that have already been used and those currently used in anesthesia.