A Case of False Positive FDG PET/CT Scan Due To Foreign Body Granuloma Mimicking Malignant Disease: Case Report

YURDAKUL A. S., Kanbay A., Gecgil E., ÖZTÜRK C.

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, vol.29, no.5, pp.1326-1329, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 5
  • Publication Date: 2009
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1326-1329
  • Gazi University Affiliated: Yes


A 61-year-old patient with a history of laryngeal carcinoma presented to the emergency room with hemoptysis. Thorax computed tomography (CT) scan demonstrated a mass with irregular margins in the right upper lobe. Fiberoptic bronchoscopy and CT-guided transthoracic biopsy revelaed no specific pathology for malignancy or infection. Fluorodeoxyglucose positron emission tomography (FDG PET)/CT scan showed an area of increased metabolic activity in the right upper lobe region [Standardized uptake value (SUV): 6.6]. The patient underwent open lung biopsy and the assessment of pathological material revealed foreign body granuloma secondary to food aspiration surrounded with chronic inflammation. Foreign body granuloma with a high standardized uptake value on FDG PET/CT scan imitates primary lung cancer or metastasis of laryngeal carcinoma. Histopatological confirmation is necessary to prevent misdiagnosis in the event of increased FDG uptake on PET imaging that may be due to a source of false positive image.