Factors Associated with Cytomegalovirus Reactivation Following Allogeneic Hematopoietic Stem Cell Transplantation: Human Leukocyte Antigens Might Be Among the Risk Factors

Acar K., Aki S. Z., ÖZKURT Z. N., BOZDAYI G., Rota S., Sucak G. T.

TURKISH JOURNAL OF HEMATOLOGY, cilt.31, sa.3, ss.276-285, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 3
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4274/tjh.2013.0244
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.276-285
  • Anahtar Kelimeler: Cytomegalovirus reactivation, Human leukocyte antigens, Allogeneic stem cell transplantation, Graft-versus-host disease, Prognosis, CMV scoring index, CYTOTOXIC T-LYMPHOCYTES, VERSUS-HOST-DISEASE, ADOPTIVE IMMUNOTHERAPY, PREEMPTIVE GANCICLOVIR, PREGNANT-WOMEN, CMV INFECTION, VIRUS, DONOR, RECIPIENT, PROPHYLAXIS
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: Cytomegalovirus (CMV) is a significant cause of morbidity and mortality in allogeneic hematopoietic stem cell transplantation (AHSCT) recipients. Current practice includes prophylactic and preemptive treatment modalities, which have risks, side effects, and costs of their own. There is no established risk scoring system that applies to all patients. We aimed to investigate the risk factors for CMV reactivation in AHSCT recipients.