Protective effect of selenium against mercury-induced toxicity on hematological and biochemical parameters of Oreochromis niloticus

Cogun H. Y., Firat Ö., Firat Ö., Yüzereroǧlu T. A., Gök G., KARGIN F., ...Daha Fazla

Journal of Biochemical and Molecular Toxicology, cilt.26, sa.3, ss.117-122, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 3
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1002/jbt.20417
  • Dergi Adı: Journal of Biochemical and Molecular Toxicology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.117-122
  • Anahtar Kelimeler: Blood parameters, Interaction, Mercury, Oreochromis niloticus, Selenium
  • Gazi Üniversitesi Adresli: Evet

Özet

In this study, to identify mercury (Hg) toxicity and whether selenium (Se) has any role in alleviation of this toxicity, it was investigated the changes in hematological and serum biochemical parameters of Oreochromis niloticus. Fish were exposed to 0.01 and 0.1 mg/L Hg and 0.01 mg/L Hg + 0.1 mg/L Se and 0.1 mg/L Hg + 1.0 mg/L Se for 7 and 14 days. The exposure of O. niloticus to Hg alone resulted in decreases in red blood cell, white blood cell, hemoglobin, hematocrit values, and cholinesterase activity while it increased in alanine aminotransferase and aspartate aminotransferase activities and cortisol and glucose levels. Se, in combination with Hg, partially or totally caused an alleviation for the toxic effect of Hg on the above mentioned hematological and biochemical parameters. The results of our study showed that Se has a protective effect against toxicity induced by Hg. © 2012 Wiley Periodicals, Inc.