Akademik Veri Yönetim Sistemi
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, cilt.22, sa.9, ss.1195-1206, 2024 (SCI-Expanded)
The gastrointestinal tract may contribute to the regulation of systemic inflamma-tion and skin diseases due to the balance between the pathogenic, opportunistic,and beneficial bacterial species it contains. External supplementation of benefi-cial bacteria, besides its known positive effect in the treatment of digestive system diseases, also has different favorable effects such as accelerated wound healing,suppression of inflammation, lower infection risk, and reduced antibiotic requi-rement. It has been reported that oral use of probiotics may be effective in thetreatment of skin diseases such as acne, psoriasis, and atopic dermatitis. Further-more, topical administration of probiotics may create a positive bacterial balance,eliminate pathological conditions, and thus have a favorable impact on the mana-gement of skin diseases. Interest in the effect of the skin microbiome and topicalprobiotics in the treatment of skin diseases has increased recently. Herein, 21 cli-nical studies and a case report in the PubMed database on the use of topicalprobiotics in dermatological diseases were evaluated