Early stage Hodgkin's disease: Experiences of erciyes university Erken evre Hodgkin hastaliǧi: Erciyes üni̇versi̇tesi̇ deneyi̇mi̇
Erciyes Tip Dergisi, cilt.24, sa.3, ss.120-125, 2002 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 24 Sayı: 3
- Basım Tarihi: 2002
- Dergi Adı: Erciyes Tip Dergisi
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.120-125
- Anahtar Kelimeler: Adult, Hodgkin disease, Therapeutics
- Gazi Üniversitesi Adresli: Hayır
Özet
Purpose: Hodgkin's disease (HD) accounts for about 1% of newly diagnosed malignant diseases annually. In this study, we evaluated the treatment of early stage HD. Patients and Method: Thirty early, stage cases out of 119 Hodgkin's disease patients were evaluated retrospectively. Stage IA, IB, and IIA were accepted as the early stage. Results: The ratio of early stage to total patients was 30/I19 (25.2%). Ten patients were stage IA, 2 patients stage IB and 18 patients stage IIA. Twenty-two patients were male, 8 patients female and the median follow up period was 30 months (range 6-120). Median age of the patients was 37.5 years (range 16-72). According to histopathological classifications, 11 patients were lymphocyte predominant type, 7 patients mixed cellularity type and 12 patients nodular sclerosing type. Radiotherapy alone was used in 20 patients. Two patients in stage IB and 7 patients in stage IIA received COPP, and 1 patient in stage IIA COPP/ABVD as the alternating regimen. Complete remission was obtained in 28 patients (93.3%). Relapse was detected in 13 (43.3%) patients and 2 died during follow up. The estimated five years overall survival rate was 90.8% and progression free survival 21.3%. Conclusion: Combined modalities with chemotherapy and radiotherapy should be used in the treatment of early stage HD.