Aging is an inevitable process. Understanding physiologic events is essential to address a disease free and healthy aging. Success can be achieved in developing new therapy modalities and enhancing quality of life in the existence of a disease which is mostly seen in that age group. We therefore tried to figure out natural effects of aging as a summary with recent data avaliable on cardiovascular system. Heart and circulatory system are divided into two categories as well as structural and cellular changes in order to clarify the subject.