Protective effect of heparin in the end organ ischemia/reperfusion injury of the lungs and heart

Gedik, HİKMET; Korkmaz, Kemal; Erdem, Havva; Karakilic, Evvah; Lafci, Gokhan; ANKARALI, HANDAN

doi:10.1186/1749-8090-7-123

Protective effect of heparin in the end organ ischemia/reperfusion injury of the lungs and heart

Gedik H. S., Korkmaz K., Erdem H., Karakilic E., Lafci G., ANKARALI H.

JOURNAL OF CARDIOTHORACIC SURGERY, cilt.7, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 7
Basım Tarihi: 2012
Doi Numarası: 10.1186/1749-8090-7-123
Dergi Adı: JOURNAL OF CARDIOTHORACIC SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Gazi Üniversitesi Adresli: Hayır

Özet

Background: Ischemia/reperfusion (I/R) injury is harmful to the cardiovascular system and is responsible for the inflammatory response and multiple organ dysfunctions. In this study we investigated the effect of activated clotting time level on the aortic cross-clamping triggers a systemic inflammatory response and it effects to lungs and heart.