Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, sa.8, ss.10-18, 2025 (TRDizin)
Abstract
Obesity is a global health problem that occurs due to the disruption of energy balance and is associated with many metabolic disorders. Adipose tissue is classified as white adipose tissue and brown adipose tissue and plays a role in the body's energy homeostasis and metabolic regulation. Each white and brown adipose tissue has different physiological and metabolic functions. Changes in the mass and function of these tissues affect glucose homeostasis and whole-body energy balance during obesity, weight loss, and subsequent processes. Beige adipocytes found in brown and white adipose tissue can potentially protect metabolic health by regulating energy balance through non-shivering thermogenesis. Certain stimuli activate this process. Recent studies have shown that omega-3 polyunsaturated fatty acids also support the formation of brown and beige adipocytes. The positive effects of omega-3 fatty acids on body composition and lipid profile have been demonstrated. It is stated that they can support fat loss, especially in individuals with obesity, diabetes, and metabolic syndrome. This review aims to examine the thermogenic effects of omega-3 fatty acids in obesity management by addressing adipose tissue and its functions.
Keywords: Obesity, Brown adipose tissue, White adipose tissue, Omega-3 fatty acids