Blood-Derived Human iPS Cells Generate Optic Vesicle-Like Structures with the Capacity to Form Retinal Laminae and Develop Synapses


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Phillips M. J., Wallace K. A., Dickerson S. J., Miller M. J., Verhoeven A. D., Martin J. M., ...More

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol.53, pp.2007-2019, 2012 (SCI-Expanded) identifier identifier identifier

Abstract

PURPOSE. We sought to determine if human induced pluripotent stem cells (iPSCs) derived from blood could produce optic vesicle-like structures (OVs) with the capacity to stratify and express markers of intercellular communication.