Blood-Derived Human iPS Cells Generate Optic Vesicle-Like Structures with the Capacity to Form Retinal Laminae and Develop Synapses


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Phillips M. J. , Wallace K. A. , Dickerson S. J. , Miller M. J. , Verhoeven A. D. , Martin J. M. , ...More

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol.53, pp.2007-2019, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53
  • Publication Date: 2012
  • Doi Number: 10.1167/iovs.11-9313
  • Title of Journal : INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
  • Page Numbers: pp.2007-2019

Abstract

PURPOSE. We sought to determine if human induced pluripotent stem cells (iPSCs) derived from blood could produce optic vesicle-like structures (OVs) with the capacity to stratify and express markers of intercellular communication.