Blood-Derived Human iPS Cells Generate Optic Vesicle-Like Structures with the Capacity to Form Retinal Laminae and Develop Synapses

Phillips, M.; Wallace, Kyle; Dickerson, Sarah; Miller, Michael; Verhoeven, Amelia; Martin, Jessica; Wright, Lynda; Shen, Wei; Capowski, Elizabeth; Perçin, FERDA; Perez, Enio; Zhong, Xiufeng; Canto-Soler, Maria; Gamm, David

doi:10.1167/iovs.11-9313

Blood-Derived Human iPS Cells Generate Optic Vesicle-Like Structures with the Capacity to Form Retinal Laminae and Develop Synapses

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Phillips M. J., Wallace K. A., Dickerson S. J., Miller M. J., Verhoeven A. D., Martin J. M., ...More

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol.53, pp.2007-2019, 2012 (SCI-Expanded)

Publication Type: Article / Article
Volume: 53
Publication Date: 2012
Doi Number: 10.1167/iovs.11-9313
Journal Name: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.2007-2019
Gazi University Affiliated: Yes

Abstract

PURPOSE. We sought to determine if human induced pluripotent stem cells (iPSCs) derived from blood could produce optic vesicle-like structures (OVs) with the capacity to stratify and express markers of intercellular communication.