Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures

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Kartal A., Kurt A. N. C., Hırfanoğlu T., Aydin K., Serdaroğlu A.

CASE REPORTS IN PEDIATRICS, 2015 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1155/2015/783936
  • Dergi Adı: CASE REPORTS IN PEDIATRICS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Gazi Üniversitesi Adresli: Evet

Özet

Subacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistentmutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cerebrospinal fluid. Subacute sclerosing panencephalitis can have atypical clinical features at the onset. Herein, we report an unusual case of subacute sclerosing panencephalitis in a childwith recurrent febrile seizures. Thedisease progressed with an appearance of myoclonic jerks, periodic high amplitude generalized complexes on EEG, and elevated titers of measles antibodies in cerebrospinal fluid leading to the final diagnosis of subacute sclerosing panencephalitis.