FGF23, alpha KLOTHO AND VITAMIN D MEDIATED CALCIUM-PHOSPHATE METABOLISM IN HAEMODIALYSIS PATIENTS


Paşaoğlu Ö. T. , Senelmis A., Helvaci O., Derici Ü. , Paşaoğlu H.

JOURNAL OF MEDICAL BIOCHEMISTRY, vol.40, no.2, pp.160-166, 2021 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.5937/jomb0-27408
  • Title of Journal : JOURNAL OF MEDICAL BIOCHEMISTRY
  • Page Numbers: pp.160-166

Abstract

Background: Klotho is a protein that acts as a co-receptor for FGF23. FGF23-Klotho axis has great importance regarding the regulation of mineral metabolism by kidneys. In this study, we analysed FGF23, Klotho, 1,25-dihydroxyvitamin D3, 25-hydroxyvitamin D, parathormone, Calcium and Phosphate levels of haemodialysis patients in order to investigate the nature of the mineral metabolism disruption in chronic kidney diseases.