FGF23, alpha-Klotho and vitamin D mediated calcium-phosphate metabolism in haemodialysis patients.
Journal of medical biochemistry, cilt.40, sa.2, ss.160-166, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 40 Sayı: 2
- Basım Tarihi: 2021
- Doi Numarası: 10.5937/jomb0-27408
- Dergi Adı: Journal of medical biochemistry
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, Central & Eastern European Academic Source (CEEAS), EMBASE, Veterinary Science Database, Directory of Open Access Journals
- Sayfa Sayıları: ss.160-166
- Gazi Üniversitesi Adresli: Evet
Özet
Background: Klotho is a protein that acts as a co-receptor for FGF23. FGF23-Klotho axis has great importance regarding the regulation of mineral metabolism by kidneys. In this study, we analysed FGF23, Klotho, 1,25-dihydroxyvitamin D3, 25-hydroxyvitamin D, parathormone, Calcium and Phosphate levels of haemodialysis patients in order to investigate the nature of the mineral metabolism disruption in chronic kidney diseases.