Proteasome Inhibition Increases the Efficiency of Lentiviral Vector-Mediated Transduction of Trabecular Meshwork


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Aktas Z., Rao H., Slauson S. R. , Gabelt B. T. , Larsen I. V. , Sheridan R. T. C. , ...More

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol.59, no.1, pp.298-310, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.1167/iovs.17-22074
  • Title of Journal : INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
  • Page Numbers: pp.298-310

Abstract

PURPOSE: To determine if proteasome inhibition using MG132 increased the efficiency of FIV vector-mediated transduction in human trabecular meshwork (TM)-1 cells and monkey organ-cultured anterior segments (MOCAS).