No association between striatal dopamine transporter binding and body mass index: A multi-center European study in healthy volunteers


van de Giessen E., Hesse S., Caan M. W. A. , Zientek F., Dickson J. C. , Tossici-Bolt L., ...Daha Fazla

NEUROIMAGE, cilt.64, ss.61-67, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.neuroimage.2012.09.011
  • Dergi Adı: NEUROIMAGE
  • Sayfa Sayıları: ss.61-67

Özet

Introduction: Dopamine is one among several neurotransmitters that regulate food intake and overeating. Thus, it has been linked to the pathophysiology of obesity and high body mass index (BM!). Striatal dopamine D-2 receptor availability is lower in obesity and there are indications that striatal dopamine transporter (DAT) availability is also decreased. In this study, we tested whether BMI and striatal DAT availability are associated.