Evaluation of ischemia after ESWL: Detection of free oxygen radical scavenger enzymes in renal parenchyma subjected to high-energy shock waves

Sarica K., Kosar A., Yaman O., Beduk Y., Durak I., Gogus O., ...Daha Fazla

UROLOGIA INTERNATIONALIS, cilt.57, sa.4, ss.221-223, 1996 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 4
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1159/000282918
  • Dergi Adı: UROLOGIA INTERNATIONALIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.221-223
  • Anahtar Kelimeler: extracorporeal shock wave lithotripsy, free oxygen radicals, ischemia, SUPEROXIDE-DISMUTASE, LITHOTRIPSY, REPERFUSION, INHIBITION, KIDNEYS
  • Gazi Üniversitesi Adresli: Evet

Özet

To evaluate the degree of ischemic formation at the tissue level after high-energy shock wave (HESW) application in a time- and dose-dependent manner, an experimental study in rabbits was performed. Following varying numbers of HESWs (1,000-2,000-3,000 shock waves) under fluoroscopic localization, treated kidneys were removed, by assessing tissue concentrations of two different free-radical scavenger enzymes (superoxide dismutase and catalase) the degree of formation of free oxygen radicals (i.e. ischemia) was evaluated. Evaluation of our results showed a statistically significant (p < 0.05) decrease in tissue scavenger enzyme levels (i.e. formation of free oxygen radicals) after 24 h following HESW application. However, results obtained 7 days after ESWL demonstrated disappearance of ischemia with normalization of tissue enzyme levels (p > 0.05).