Bilateral Optic Pathway Ganglioglioma: The Fifth Case in the Literature

Karaaslan B., UÇAR M., Kulduk G., BÖRCEK A. Ö., Baykaner M. K.

PEDIATRIC NEUROSURGERY, cilt.51, sa.1, ss.48-54, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1159/000439541
  • Dergi Adı: PEDIATRIC NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.48-54
  • Anahtar Kelimeler: Ganglioglioma, Optic tract, Visual field defect, Suprasellar tumor, Histopathology, CENTRAL-NERVOUS-SYSTEM, OF-THE-LITERATURE, LOW-GRADE GLIOMAS, FOLLOW-UP, SUPRATENTORIAL GANGLIOGLIOMAS, NEUROFIBROMATOSIS, CHIASM, TUMOR, EPILEPSY, PATIENT
  • Gazi Üniversitesi Adresli: Evet

Özet

Gangliogliomas are mixed tumors which contain both glial and neuronal elements. The optic pathway is a very rare location for gangliogliomas, with less than 23 cases reported in the literature. Bilateral involvement of the entire optic pathway was reported in only 4 cases before. Because of similar radiological appearance of other pathological entities such as gliomas and craniopharyngiomas, histopathological diagnosis is essential. We report a ganglioglioma case that involved both optic pathways. A 12-year-old patient suffering from visual deterioration for 6 months was evaluated. After a visual field test and radiological examinations, a microsurgical biopsy procedure was performed. Pathological examination revealed dysplastic/neoplastic ganglion cells and neoplastic glial cells, and the diagnosis was a World Health Organization (WHO) grade 1 ganglioglioma. The patient is scheduled for adjuvant radiotherapy with the hope of prevention of progression. (C) 2015 S. Karger AG, Basel