Neutrophil CD64 expression in Behcet's disease

Ureten K., Ertenli I., Ozturk M., Kiraz S., Onat M., Tuncer M., ...Daha Fazla

JOURNAL OF RHEUMATOLOGY, cilt.32, sa.5, ss.849-852, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 5
  • Basım Tarihi: 2005
  • Dergi Adı: JOURNAL OF RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.849-852
  • Anahtar Kelimeler: Behcet's disease, disease activation, CD64, neutrophil, FC-GAMMA-RI, RECEPTORS, SERUM, PENICILLIN, INFECTION, CYTOKINES, SYMPTOMS, PROTEIN, CELLS, MICE
  • Gazi Üniversitesi Adresli: Hayır

Özet

Objective. Hyperfunction of neutrophils is a characteristic finding in Behcet's disease (BD). Microbial agents have been proposed as causative agents in the disease flares. Fc gamma receptor 1 (CD64) is not normally expressed by neutrophils of healthy individuals, but is upregulated by these cells in response to microbial wall components and proinflammatory cytokines. The degree of polymorphonuclear leukocyte (PMN) CD64 expression is different in autoimmune diseases and systemic infectious diseases. We investigated PMN CD64 expression in patients with BD.