Vaginal permeability and enzymatic activity studies in normal and ovariectomized rabbits

Acarturk F., Robinson J.

PHARMACEUTICAL RESEARCH, vol.13, no.5, pp.779-783, 1996 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 5
  • Publication Date: 1996
  • Doi Number: 10.1023/a:1016016120392
  • Journal Name: PHARMACEUTICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.779-783
  • Keywords: vaginal permeability, enzymatic activity, ovariectomized rabbits, enkephalin derivative, ABSORPTIVE MUCOSAE, DRUG DELIVERY, ESTROUS-CYCLE, ALBINO RABBIT, RATS, PEPTIDE, ROUTE
  • Gazi University Affiliated: Yes

Abstract

Purpose. This study was initiated to develop an animal model, using ovariectomized rabbits, for the post-menopausal human, based on in vitro vaginal tissue permeability and aminopeptidase activity.