The role of GSTM1, GSTT1, GSTP1, and OGG1 polymorphisms in type 2 diabetes mellitus risk: A case-control study in a Turkish population

Gonul N., KADIOĞLU E., Kocabas N. A., ÖZKAYA M., Karakaya A. E., KARAHALİL B.

GENE, cilt.505, sa.1, ss.121-127, 2012 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 505 Sayı: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.gene.2012.05.025
  • Dergi Adı: GENE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.121-127
  • Anahtar Kelimeler: Type 2 diabetes mellitus, GSTM1, GSTT1, GSTP1, OGG1 Ser326Cys, Oxidative stress, GLUTATHIONE-S-TRANSFERASE, GENETIC POLYMORPHISMS, SUSCEPTIBILITY, ASSOCIATION, REPAIR, T1
  • Gazi Üniversitesi Adresli: Evet

Özet

The aim of the present study was to investigate the role of some polymorphisms in GSTs (GSTM1,GSTT1 and GSTP1) which are very important protective mechanisms against oxidative stress and in OGG1 gene which is important in DNA repair, against the risk of type 2 diabetes mellitus (T2DM).