Dramatic response of a patient with pregnancy induced idiopathic pulmonary arterial hypertension to sildenafil treatment

Tacoy G., Ekim N. N., Cengel A.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, cilt.36, sa.2, ss.414-417, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 2
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1111/j.1447-0756.2009.01136.x
  • Dergi Adı: JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.414-417
  • Anahtar Kelimeler: idiopathic pulmonary arterial hypertension, pregnancy, sildenafil, treatment, ORAL SILDENAFIL, THERAPY, EPOPROSTENOL, HEART
  • Gazi Üniversitesi Adresli: Evet

Özet

Idiopathic pulmonary arterial hypertension (IPAH) is characterized by a progressive increase in pulmonary vascular resistance, which may lead to right ventricular failure and death. Major cardiovascular and pulmonary alterations occur during pregnancy and therefore worsen or increase the complications of pulmonary arterial hypertension (PAH). A patient diagnosed with IPAH after a successful full-term pregnancy and cesarean section with epidural anesthesia is presented. The postoperative course was complicated by progressive dyspnea, and lower limb edema. The outcome of treatment with sildenafil during puerperium was favorable in this patient. The clinical course was complicated by an unexpected spontaneous pregnancy after primary infertility.