Preliminary screening of acetylcholinesterase inhibitory and antioxidant activities of Anatolian Heptaptera species

Creative Commons License

ŞENOL DENİZ F. S., Yilmaz G., Sener B., KOYUNCU M., ERDOĞAN ORHAN İ.

PHARMACEUTICAL BIOLOGY, vol.48, no.3, pp.337-341, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.3109/13880200903133837
  • Journal Name: PHARMACEUTICAL BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.337-341
  • Keywords: Heptaptera, Umbelliferae, acetylcholinesterase inhibition, antioxidant, total phenol content, DERIVATIVES, COUMARIN
  • Gazi University Affiliated: Yes

Abstract

The ethyl acetate and methanol extracts prepared from the fruits, aerial parts, and roots of Heptaptera anatolica (Boiss.) Tutin, (Umbelliferae), H. anisoptera (DC.) Tutin, H. cilicica (Boiss. & Balansa) Tutin (endemic), and H. triquetra (Vent.) Tutin were tested for their acetylcholinesterase (AChE) inhibitory and antioxidant activities. AChE inhibition was evaluated using ELISA microplate reader at 500, 1000, and 2000 mu g mL