Preliminary screening of acetylcholinesterase inhibitory and antioxidant activities of Anatolian Heptaptera species

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ŞENOL DENİZ F. S., Yilmaz G., Sener B., KOYUNCU M., ERDOĞAN ORHAN İ.

PHARMACEUTICAL BIOLOGY, cilt.48, sa.3, ss.337-341, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 3
  • Basım Tarihi: 2010
  • Doi Numarası: 10.3109/13880200903133837
  • Dergi Adı: PHARMACEUTICAL BIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.337-341
  • Anahtar Kelimeler: Heptaptera, Umbelliferae, acetylcholinesterase inhibition, antioxidant, total phenol content, DERIVATIVES, COUMARIN
  • Gazi Üniversitesi Adresli: Evet

Özet

The ethyl acetate and methanol extracts prepared from the fruits, aerial parts, and roots of Heptaptera anatolica (Boiss.) Tutin, (Umbelliferae), H. anisoptera (DC.) Tutin, H. cilicica (Boiss. & Balansa) Tutin (endemic), and H. triquetra (Vent.) Tutin were tested for their acetylcholinesterase (AChE) inhibitory and antioxidant activities. AChE inhibition was evaluated using ELISA microplate reader at 500, 1000, and 2000 mu g mL