Thymosin beta-4 overexpression correlates with high-risk groups in gastric gastrointestinal stromal tumors: A retrospective analysis by immunohistochemistry

ŞAHİN S., EKİNCİ Ö., Seckin S., DURSUN A.

PATHOLOGY RESEARCH AND PRACTICE, cilt.213, sa.9, ss.1139-1143, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 213 Sayı: 9
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.prp.2017.07.005
  • Dergi Adı: PATHOLOGY RESEARCH AND PRACTICE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1139-1143
  • Anahtar Kelimeler: Clinicopathological features, Thymosin beta-4, Gastric gastrointestinal stromal tumor, Immunohistochemistry, EXPRESSION, PROLIFERATION, MUTATIONS, DIAGNOSIS, IMATINIB, DNA
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Thymosin beta-4 (T beta 4) is a protein that is linked to a number of important biological actions and recently tumor progression and poor prognosis of some tumors. The aim of this study was to evaluate T beta 4 expression in gastric GISTs and correlate with some clinicopathological characteristics related with prognosis and clinical outcome in order to add further data to the current literature.