Metoclopramide inhibits trigeminovascular activation: evidence for effective acute attack treatment in migraine

Doganay Aydin H., VURALLI D. , AKÇALI D. T. , Bolay H. B.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.47, sa.1, ss.343-347, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Konu: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3906/sag-1601-195
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Sayfa Sayıları: ss.343-347

Özet

Background/aim: Metoclopramide is an effective and commonly used medication in acute migraine treatment but an experimental evidence base is lacking. We aimed to investigate the antimigraine effect of metoclopramide in a migraine model and whether the analgesic effect of metoclopramide was likely to be D-2 receptor-mediated.