Diverse Responses of Neurons and Monocytes to Titanium Dioxide Nanoparticle Exposure


ENGİN A. B. , ENGİN E. D.

TURKISH JOURNAL OF IMMUNOLOGY, vol.7, no.1, pp.40-49, 2019 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.25002/tji.2019.1037
  • Title of Journal : TURKISH JOURNAL OF IMMUNOLOGY
  • Page Numbers: pp.40-49

Abstract

Introduction: The toxicity of titanium dioxide nanoparticles (TiO(2)NPs) in neurons occurs by glutamate signaling via N-methyl-d-aspartate (NMDA) receptors. Although cellular uptake of TiO(2)NPs may lead to oxidative stress in macrophages, it is nor known whether TiO(2)NPs have toxic effects on U937 monocytic cell line.