Diverse Responses of Neurons and Monocytes to Titanium Dioxide Nanoparticle Exposure

ENGİN A. B., ENGİN E. D.

TURKISH JOURNAL OF IMMUNOLOGY, cilt.7, sa.1, ss.40-49, 2019 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.25002/tji.2019.1037
  • Dergi Adı: TURKISH JOURNAL OF IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.40-49
  • Gazi Üniversitesi Adresli: Evet

Özet

Introduction: The toxicity of titanium dioxide nanoparticles (TiO(2)NPs) in neurons occurs by glutamate signaling via N-methyl-d-aspartate (NMDA) receptors. Although cellular uptake of TiO(2)NPs may lead to oxidative stress in macrophages, it is nor known whether TiO(2)NPs have toxic effects on U937 monocytic cell line.