Flow cytometric DNA analysis, and immunohistochemical p53, PCNA and histopathologic study in primary achalasia: preliminary results.

Bektas A., Yasa M., Kuzu I., Dogan İ. , ÜNAL S., Ormeci N.

Hepato-gastroenterology, cilt.48, sa.38, ss.408-12, 2001 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Konu: 38
  • Basım Tarihi: 2001
  • Dergi Adı: Hepato-gastroenterology
  • Sayfa Sayıları: ss.408-12


Background/Aims: Primary achalasia Is a premalignant disorder of the esophagus. The studies for esophageal cancer pathogenesis may reveal early diagnosis of esophageal cancer. DNA aneuploidy, p53 mutations and cellular proliferation are important factors in cancer development. As far as we know, we have not encountered any study on these factors in achalasia.