The delta fractional flow reserve can predict lesion severity and long-term prognosis

Kocaman S. A. , ŞAHİNARSLAN A. , Arslan U., Timurkaynak T.

ATHEROSCLEROSIS, vol.203, no.1, pp.178-184, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 203 Issue: 1
  • Publication Date: 2009
  • Doi Number: 10.1016/j.atherosclerosis.2008.06.009
  • Title of Journal : ATHEROSCLEROSIS
  • Page Numbers: pp.178-184
  • Keywords: Fractional flow reserve, Lesion severity, Long-term prognosis, Intermediate lesion, Coronary artery disease, BLOOD-FLOW, CORONARY, INTRACORONARY, VARIABILITY, ADENOSINE, DISEASE


Background: Fractional flow reserve (FFR) is a method which is used to identify the angiographically intermediate lesions requiring revascularization. However, physiological importance and clinical usability of delta (Delta) FFR, the difference between FFR in baseline conditions (FFRbase, resting) and after adenosine administration (FFRmin, hyperemic), is currently unknown. We aimed to investigate whether Delta FFR may be helpful in the identification of the lesion severity and predictability of long term prognosis.