The Effect of Exopolysaccharide-Producing Probiotic Strains on Gut Oxidative Damage in Experimental Colitis

Sengul N., Isik S., ASLIM B., UÇAR G., Demirbag A. E.

DIGESTIVE DISEASES AND SCIENCES, cilt.56, sa.3, ss.707-714, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 56 Sayı: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1007/s10620-010-1362-7
  • Dergi Adı: DIGESTIVE DISEASES AND SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.707-714
  • Anahtar Kelimeler: Inflammatory bowel disease, Exopolysaccharides, Probiotic, Oxidative damage, INFLAMMATORY-BOWEL-DISEASE, LACTIC-ACID BACTERIA, OXYGEN, GLUTATHIONE, STRESS, RATS, METABOLITES, MICROFLORA, DEFENSE, MILK
  • Gazi Üniversitesi Adresli: Evet

Özet

Oxidative stress plays a role in disease initiation and progression in inflammatory bowel disease (IBD) and manipulation of this pathway may attenuate disease progress. In this study, the effect of exopolysaccharide (EPS)-producing probiotic bacteria on gut oxidative damage was evaluated in a rat model of experimental colitis.