DNA Methylation Dynamics in Human Carotid Plaques After Cerebrovascular Events

Zaina, Silvio; Goncalves, Isabel; Javier Carmona, F.; Gomez, Antonio; Heyn, Holger; Mollet, Ines; Moran, Sebastian; Varol, NURAY; Esteller, Manel

doi:10.1161/atvbaha.115.305630

DNA Methylation Dynamics in Human Carotid Plaques After Cerebrovascular Events

Zaina S., Goncalves I., Javier Carmona F., Gomez A., Heyn H., Mollet I. G., ...Daha Fazla

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, cilt.35, sa.8, ss.1835-1842, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 35 Sayı: 8
Basım Tarihi: 2015
Doi Numarası: 10.1161/atvbaha.115.305630
Dergi Adı: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1835-1842
Anahtar Kelimeler: atherosclerosis, CpG islands, DNA methylation, human, oxidative stress, EPIGENOME-WIDE ASSOCIATION, LIPID-LOWERING DRUGS, ATHEROSCLEROTIC LESIONS, GENE-EXPRESSION, DIET NETWORK, KAPPA-B, INFLAMMATION, HYPOMETHYLATION, ACTIVATION, CELLS
Gazi Üniversitesi Adresli: Evet

Özet

Objective To understand whether cerebrovascular events, a major complication of atherosclerosis, are associated with any specific DNA methylation changes in the carotid plaque.