Results of native and transplant kidney biopsies of children in a single center over a 15 years period.

Creative Commons License

Isiyel E., Fidan K., BÜYÜKKARAGÖZ B., Akcaboy M., Kandur Y., IŞIK GÖNÜL İ., ...More

Renal failure, vol.39, no.1, pp.702-706, 2017 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.1080/0886022x.2017.1398094
  • Journal Name: Renal failure
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.702-706
  • Gazi University Affiliated: Yes


Renal biopsy is an important diagnostic procedure in pediatric nephrology. This study retrospectively investigates the indications, results and complications in a single tertiary children's hospital in Turkey. We evaluated the native and transplant kidney biopsies in Gazi University Pediatric Nephrology Department between 2001 and 2015. A total of 196 biopsies (144 natives and 52 transplants) were included into the study. The mean age of the patients was respectively 10.8 +/- 3.5, 13.9 +/- 1.5years. The main indication for a biopsy was non-nephrotic proteinuria with or without hematuria (n=35), followed by steroid-resistance nephrotic syndrome (SRNS) (n=34) and Henoch-Schonlein purpura (HSP)-related proteinuria (n=20) for native kidneys. We found that focal segmental glomerulosclerosis (FSGS) (11.7%) was the most common histopathologic diagnosis for native kidneys, but acute cellular rejection (7.6%) was the most common histopathologic diagnosis for transplant kidneys. The complication rate in our study was founded 6.6% totally. Different complication rates were found in other studies; however, we think that this difference comes from the inspecting methodology of the complications. Hence, we wanted to share our own experience in the context of other studies in the literature.