Biological Activity Studies of Some Synthesized Novel Furan and Pyran Derivatives

Sari E., Aslan H., Dadi S., Oktemer A., Logoglu E.

GAZI UNIVERSITY JOURNAL OF SCIENCE, vol.30, no.4, pp.49-55, 2017 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 4
  • Publication Date: 2017
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.49-55
  • Keywords: Antibacterial activity, Antifungal activity, Furan, Pyran, ANTIMICROBIAL AGENTS, PIRONETIN
  • Gazi University Affiliated: Yes


In this study, some novel furan and pyran derivatives were synthesized as mentioned in our previous report [1]. The novel furan and pyran derivatives were investigated for antibacterial activity against gram-positive/negative bacteria and fungus. The antibacterial and antifungal activities were determined by the disc diffusion method (DISC) and minimum inhibition concentration (MIC) against the tested bacteria and fungus. The inhibition zones were compared with those of reference discs which were studied in our previous work [2]. Reference discs used for control were as follows ketoconazole, ampicillin, tetracycline, penicillin, chloramphenicol, and gentamicin. From the results it could be said that some of the chemical compound can be used as a raw medicine sources.