Biological Activity Studies of Some Synthesized Novel Furan and Pyran Derivatives

Sari E., Aslan H., Dadi S., Oktemer A., Logoglu E.

GAZI UNIVERSITY JOURNAL OF SCIENCE, cilt.30, sa.4, ss.49-55, 2017 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 4
  • Basım Tarihi: 2017
  • Dergi Adı: GAZI UNIVERSITY JOURNAL OF SCIENCE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.49-55
  • Anahtar Kelimeler: Antibacterial activity, Antifungal activity, Furan, Pyran, ANTIMICROBIAL AGENTS, PIRONETIN
  • Gazi Üniversitesi Adresli: Evet

Özet

In this study, some novel furan and pyran derivatives were synthesized as mentioned in our previous report [1]. The novel furan and pyran derivatives were investigated for antibacterial activity against gram-positive/negative bacteria and fungus. The antibacterial and antifungal activities were determined by the disc diffusion method (DISC) and minimum inhibition concentration (MIC) against the tested bacteria and fungus. The inhibition zones were compared with those of reference discs which were studied in our previous work [2]. Reference discs used for control were as follows ketoconazole, ampicillin, tetracycline, penicillin, chloramphenicol, and gentamicin. From the results it could be said that some of the chemical compound can be used as a raw medicine sources.