Antibacterial, antifungal and enzyme inhibitory effects of selected plants from Turkey

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Gürbüz İ., Özçelik B., Günbatan T., Akkol E., Sahinoz M., Akaydın G.

PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol.34, no.3, pp.1011-1017, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.36721/pjps.2021.34.3.reg.1011-1017.1
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.1011-1017
  • Keywords: Antibacterial activity, antifungal activity, antihyaluronidase activity, antielastase activity, anticollagenase activity, ELASTASE ACTIVITY, ANTIOXIDANT, LEAVES, BARK, L.
  • Gazi University Affiliated: Yes


In this study, antibacterial, antifungal, antihyaluronidase, anticollagenase and antielastase activity of Hypericum bithynicum, Malva neglecta, Morus alba, Rubus discolor, Sambucus ebulus and Smilax excelsa were investigated. Methanol extracts of M. neglecta and R. discolor and all extracts of H. bithynicum were more active against Staphylococcus epidermidis. Similarly, water extracts of M. alba and S. ebulus were more active against Streptococcus pneumonia. Additionally, S. ebulus and S. excelsa had prominent antifungal activity on Candida albicans. Besides, methanol extract of M. neglecta and n-hexane extract of H. bithynicum were detelinined to have significant antihyaluronidase activity. Only R. discolor showed significant antielastase effect.