Effects of scaling and root planing and sub-antimicrobial dose doxycycline on oral and systemic biomarkers of disease in patients with both chronic periodontiti and coronary artery disease

Tueter, GÜLAY; Kurtis, MAZLUM; SERDAR, Muhittin; Aykan, Tuba; Okyay, Kaan; Yuecel, AYŞEGÜL; Toyman, Utku; Pinar, Selin; Cemri, Mustafa; Cengel, ATİYE; Walker, Stephen; Golub, Lorne

doi:10.1111/j.1600-051x.2007.01104.x

Effects of scaling and root planing and sub-antimicrobial dose doxycycline on oral and systemic biomarkers of disease in patients with both chronic periodontiti and coronary artery disease

Tueter G., Kurtis B., SERDAR M. A., Aykan T., Okyay K., Yuecel A., ...Daha Fazla

JOURNAL OF CLINICAL PERIODONTOLOGY, cilt.34, sa.8, ss.673-681, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 34 Sayı: 8
Basım Tarihi: 2007
Doi Numarası: 10.1111/j.1600-051x.2007.01104.x
Dergi Adı: JOURNAL OF CLINICAL PERIODONTOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.673-681
Anahtar Kelimeler: adjunctive treatment, cardiovascular disease, C-reactive protein, gingival crevicular fluid/analysis, host modulation therapy, matrix metalloproteinases, periodontitis/therapy, plasma lipids, subantimicrobial dose doxycycline, C-REACTIVE PROTEIN, GINGIVAL CREVICULAR FLUID, MATRIX-METALLOPROTEINASE INHIBITOR, MYOCARDIAL-INFARCTION, INFLAMMATORY MARKERS, COLLAGENASE ACTIVITY, TREPONEMA-DENTICOLA, ADULT PERIODONTITIS, RISK, INFECTIONS
Gazi Üniversitesi Adresli: Evet

Özet

Objectives: This study evaluated the effects of scaling and root planing (SRP) +/- sub-antimicrobial dose doxycycline (SDD) on gingival crevicular fluid (GCF) levels of matrix metalloproteinase (NIMP) -1, -8, -13 and on serum levels of high-sensitivity C-reactive protein (HsCRP) and lipid fractions in patients with both chronic periodontitis (CP) and coronary artery disease (CAD).