Changes of sFas and sFasL, oxidative stress markers in serum and follicular fluid of patients undergoing IVF

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Pekel A., GÖNENÇ A., Turhan N. O., Kafali H.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, cilt.32, sa.2, ss.233-241, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1007/s10815-014-0396-8
  • Dergi Adı: JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.233-241
  • Anahtar Kelimeler: sFas, sFasL, Oxidative stress, Antioxidant, IVF, IN-VITRO FERTILIZATION, SOLUBLE FAS LIGAND, SUPEROXIDE-DISMUTASE, ASSISTED REPRODUCTION, ANTIOXIDANT CAPACITY, WOMEN, APOPTOSIS, OXYGEN, ENDOMETRIOSIS, INFERTILITY
  • Gazi Üniversitesi Adresli: Evet

Özet

The Fas-Fas Ligand interaction is one of the essential events for the induction of apoptosis whereas the exact role of their soluble forms in the reproductive system is still not fully understood. Also oxidative stress in the pathogenesis of infertility causing diseases in women and has been suggested as one of the important factors that negatively affect IVF outcome. In this study, our aim was to evaluate serum and follicular fluid levels of soluble Fas soluble Fas Ligand, malondialdehyde, superoxide dismutase and total antioxidant capacity in patients undergoing IVF and compared with controls.