Alzheimer's Disease and Protein Kinases

ENGİN A. B. , ENGİN A.

PROTEIN KINASE-MEDIATED DECISIONS BETWEEN LIFE AND DEATH, vol.1275, pp.285-321, 2021 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 1275
  • Publication Date: 2021
  • Doi Number: 10.1007/978-3-030-49844-3_11
  • Title of Journal : PROTEIN KINASE-MEDIATED DECISIONS BETWEEN LIFE AND DEATH
  • Page Numbers: pp.285-321

Abstract

Alzheimer's disease (AD) is the most common neurodegenerative disorder and accounts for more than 60-80% of all cases of dementia. Loss of pyramidal neurons, extracellular amyloid beta (Abeta) accumulated senile plaques, and neurofibrillary tangles that contain hyperphosphorylated tau constitute the main pathological alterations in AD.